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Title: Strong evidence linking Aluminium and Alzheimer’s
Source:
The Hippocratic Post
URL Source: http://www.hippocraticpost.com/ment ... -linking-aluminium-alzheimers/
Published: Dec 15, 2016
Author: Professor Chris Exley
Post Date: 2016-12-19 09:48:40 by cranky
Keywords: None
Views: 3570
Comments: 14
There has been a strong link between human exposure to aluminium and the incidence of Alzheimer’s disease for half a century or more. However, without definite proof, there is still no consensus in the scientific community about the role of this known neurotoxin in this devastating brain disease.
The latest research from my group, published in the Journal of Trace Elements in Medicine and Biology, makes this link even more compelling. In my view, the findings are unequivocal in their confirmation of a role for aluminium in some if not all Alzheimer’s disease.
At the very least, these new results should encourage everyone and even those who have steadfastly maintained that aluminium has no role in the disease to think again.
I don’t believe that is the only factor, but I think it is an important one which should be considered very seriously.
When our new results are put into the context of what is already known about aluminium and Alzheimer’s disease their significance becomes overwhelming and compelling.
We already know that the aluminium content of brain tissue in late-onset or sporadic Alzheimer’s disease is significantly higher than is found in age-matched controls. So, individuals who develop Alzheimer’s disease in their late sixties and older also accumulate more aluminium in their brain tissue than individuals of the same age without the disease.
Even higher levels of aluminium have been found in the brains of individuals, diagnosed with an early-onset form of sporadic (usually late onset) Alzheimer’s disease, who have experienced an unusually high exposure to aluminium through the environment (e.g. Camelford) or through their workplace. This means that Alzheimer’s disease has a much earlier age of onset, for example, fifties or early sixties, in individuals who have been exposed to unusually high levels of aluminium in their everyday lives.
We now show that some of the highest levels of aluminium ever measured in human brain tissue are found in individuals who have died with a diagnosis of familial Alzheimer’s disease.
The levels of aluminium in brain tissue from individuals with familial Alzheimer’s disease are similar to those recorded in individuals who died of an aluminium-induced encephalopathy while undergoing renal dialysis.
In support of our quantitative data, we have also used a recently developed and fully validated method of fluorescence microscopy to provide stunning and unequivocal images of aluminium in brain tissue from familial Alzheimer’s disease donors.
Familial Alzheimer’s disease is an early-onset form of the disease with first symptoms occurring as early as 30 or 40 years of age. It is extremely rare, perhaps 2-3% of all cases of Alzheimer’s disease. Its bases are genetic mutations associated with a protein called amyloid-beta, a protein which has been heavily linked with the cause of all forms of Alzheimer’s disease.
Individuals with familial Alzheimer’s disease produce more amyloid beta and the onset of the symptoms of Alzheimer’s disease are much earlier in life.
This new research may suggest that these genetic predispositions to early onset Alzheimer’s disease are linked in some way to the accumulation of aluminium (through ‘normal’ everyday human exposure) in brain tissue.
Ageing is the main risk factor for Alzheimer’s disease and aluminium accumulates in human brain tissue with ageing. Environmental or occupational exposure to aluminium results in higher levels of aluminium in human brain tissue and an early onset form of sporadic Alzheimer’s disease. The genetic predispositions which are used to define familial or early-onset Alzheimer’s disease also predispose individuals to higher levels of brain aluminium at a much younger age.
Aluminium is accepted as a known neurotoxin, for example being the cause of dialysis encephalopathy, and its accumulation in human brain tissue at any age can only contribute to any ongoing disease state or toxicity.
We should take all possible precautions to reduce the accumulation of aluminium in our brain tissue through our everyday activities and we should start to do this as early in our lives as possible.
The new research, published in the Journal of Trace Elements in Medicine and Biology is available online and open access (http://www.sciencedirect.com/science/article/pii/S0946672X16303777) (1 image)
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Do we acquire aluminum in our bodies by drinking from aluminum cans, or frying in aluminum pans? I would guess the answer is yes from the pans, and maybe from the cans.
Exercising rights is only radical to two people, Tyrants and Slaves. Which are YOU? Our ignorance has driven us into slavery and we do not recognize it.
#2. To: jeremiad (#1)
Do we acquire aluminum in our bodies by drinking from aluminum cans, or frying in aluminum pans? I would guess the answer is yes from the pans, and maybe from the cans.
Definitely from frying in aluminium pans, especially if the food is acidic, like tomatos. I understand in the middle ages that tomatoes were considered mildly poisonous and were avoided, but that was because dinner plates were made of lead, and the acid in the tomatoes was dissolving the lead which in the longer term led to lead poisoning.
Aluminum is also a soft metal so it's relatively easy to scrape trace amounts of with spatula's and other cooking utensils.
IMO aluminum cooking pans and pots should be recycled into something else.
As for sodas, not so much as I think cans are lined so the aluminum is not in direct contact with the drink. However, the lining contains BPH which is also bad for you.
#3. To: cranky (#0)
Does this mean I shouldn't gnaw on the siding anymore?
#4. To: Hank Rearden (#3)
No more aluminum siding gnawing for you Hank. Switch to vinyl siding though, and you can continue if you must. It only has lead in it.
Exercising rights is only radical to two people, Tyrants and Slaves. Which are YOU? Our ignorance has driven us into slavery and we do not recognize it.
#5. To: cranky (#0)
"Strong evidence linking Aluminium and Alzheimer’s"
I believe it.
#6. To: jeremiad (#1)
frying in aluminum pans?
My Mom 40 years ago would not cook much in aluminum pans and if she did she would us wooden spoons to stir what she was cooking so as not to scratch the aluminum.
I do not go to church every time the doors are opened, but I love Jesus Christ. I am only human and fail Him daily. I believe Jesus is the Son of God, was born of a virgin, was crucified on a cross, died for my sins and rose from the dead and that He loves us dearly, and is faithful to forgive us of our sins. But He says that if you deny me in front of your friends I will deny you in front of my Father. Can I get an Amen!
#7. To: U don't know me (#6)
put
goldfish
in
a
bowl
of
water
that
was
boiled
in
a
aluminum
pan
they
will
die
read
this
in
woman's
magazine
40
years
ago
love
boris
If you ... don't use exclamation points --- you should't be typeing ! Commas - semicolons - question marks are for girlie boys !
#8. To: BorisY (#7)
It figures that you were reading wimmens magazines 40 years ago, Banjo Boy.
#9. To: Fred Mertz (#8)
there
was
probably
a
lead
water
line
pipe
that
went
to
your
childhood
home
love
boris
If you ... don't use exclamation points --- you should't be typeing ! Commas - semicolons - question marks are for girlie boys !
#10. To: BorisY (#9)
We had plaster with horse hair mixed in on our walls. Placed onto wooden slats and then eventually covered with about 5 layers of (ugly) wallpaper.
I believe the first part of the home was built in 1805, Banjo Boy.
#11. To: Fred Mertz (#10)
wooden slats
lathe
on
a
federal
building
I
was
a
union
lather
insulation
work
metal
mesh
lathe
on
duct
work
some
apts
too
for
stucco
love
boris
ps
in
my
childhood
home
I
think
there
was
asbestos
insulation
on
our
hot
water
heating
basement
piping
If you ... don't use exclamation points --- you should't be typeing ! Commas - semicolons - question marks are for girlie boys !
#12. To: jeremiad (#1)
I would guess the answer is yes from the pans, and maybe from the cans.
I would guess the same.
#13. To: U don't know me (#6)
My Mom 40 years ago would not cook much in aluminum pans and if she did she would us wooden spoons to stir what she was cooking so as not to scratch the aluminum.
An interesting precaution.
I wonder if it had any practical effect.
But I bet it couldn't hurt.
#14. To: U don't know me (#6)
"If you will confess me openly, I too will confess openly to my Father that you are mine" poorly paraphrased I am sure, but you get the drift.
I give you a hearty AMEN.
Exercising rights is only radical to two people, Tyrants and Slaves. Which are YOU? Our ignorance has driven us into slavery and we do not recognize it.
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